This time it is for a first-in-human immunology and inflammation candidate, EXS4318, which inhibits the PKC theta kinase that we know to play a critical role in controlling T cell function.
Our portfolio company, Exscientia, announced the start of its fourth clinical trial.
With co-authors from the Profluent team Richard Socher (ex-chief scientist at Salesforce) and James Fraser (Bioengineering professor at UCSF) and other collaborators, they published their findings in an article published by Nature Biotechnology: Large language models generate functional protein sequences across diverse families. Ali had previously led Salesforces’ moonshot project ProGen, during which his team showed in pioneering work how language models can be adapted to be a controllable tool to design proteins with predictable functions. This month, we announced our investment into Profluent, a new AI-first protein design company founded and led by Ali Madani. Ugur Sahin, CEO of BioNTech.Īt Air Street Capital, we continue to be bullish on the sector-wide overhauling of biotech to be AI-first by design. This deal sees BioNTech deepen its commitment to weaving increasingly capable AI systems throughout its workflows: “Our aim is to make BioNTech a technology company where AI is seamlessly integrated into all aspects of our work.”, Prof. A year later, BioNTech and InstaDeep collaborated to produce a successful early warning system to detect potential high-risk Covid variants by making use of related approaches (see slide 65 from State of AI Report 2022 below). Astute readers of this newsletter will recall that in our Jan 2021 issue, we wrote about a Science paper demonstrating how language models could learn the language of viral evolution and escape. In the last few years, InstaDeep has also made strides in machine learning-based protein design by adding DeepChain, a protein design platform, to its portfolio of products.
MYST AI CRUNCHBASE SERIES
Largely bootstrapped until it raised a $7M Series A in 2019 and a $100M Series B in 2021, the company worked with teams on the earlier side of AI deployment (such as Deutsche Bahn, the largest rail operator in Europe) to companies with leading AI teams (such as Google and NVIDIA). InstaDeep was born in 2015 with a mission to bring state of the art decision making AI systems into the enterprise. Register for next year’s RAAIS, a full-day event in London that explores research frontiers and real-world applications of AI-first technology at the world’s best companies.Īs usual, we love hearing what you’re up to and what’s on your mind, just hit reply or forward to your friends :-)īioNTech acquired London and Tunis-based AI startup InstaDeep for $680M (cash + stock) - this was a huge deal. The State of AI Report provided two key figures to The Economist’s piece on The race of the AI labs heats up. Nathan commented on The Financial Times’ Big Read on The growing tensions around spinouts at British universities. The Times Higher Education profiled our open source data term database, spinout.fyi. Nathan wrote an oped in The Times for why university spinouts are a critical engine for our technology industry and why spinout policy needs urgent reform. Before we kick off, a couple of news items from us :-) This one is a monster so it might get clipped in your inbox (read the online version in case!). For humans accustomed to doing the tasks that AI now promises to either make easier or take over altogether, the process should be both intriguing and nerve-wracking.Welcome to the latest issue of your guide to AI, an editorialized newsletter covering key developments in AI research, industry, geopolitics and startups during January 2023. In the case of enterprise AI tools, it’s safe to presume those at the early stages are equally early in drumming up sales.īut as the buzz around AI intensifies, we’re expecting 2023 to be a year of increasing enterprise adoption, and not just headline generation. The trouble with covering startups, as opposed to public companies, is they are under no obligation to disclose just how much revenue they’re generating. Meanwhile Retail Rocket, a Dutch company developing AI-enabled marketing automation tools, is one of the more sizable early-stage funding recipients, with a $24 million Series A last summer. Forethought, which describes itself as a generative AI provider for customer service automation, is particularly well-funded, having raised $92 million to date.
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